MAIIA Diagnostics
Erythropoietin Research
Ultrasensitive Lateral Flow Tests
Urine Analysis

Carbon Black Nano-Strings

The unique Carbon Black Nano-Strings (CBNS) from MAIIA Diagnostics can be used as ultra-sensitive labels for quantitative immuno-chromatographic (lateral flow) and array tests, as an alternative to gold, colored latex and fluorescent particles.

Coloured particles, for example gold and blue polystyrene, are widely used as a means to visually detect and quantify various analytes in different immunoassays.

CBNS consist of carbon particles combined into elongated primary aggregates, which can easily bind antibodies and other substances to their large surface area. Compared to other particles, they give higher signal intensity, making possible the development of ultra-sensitive tests suitable for low concentration analytes.

The grey or black signal achieved can be read with instruments like ordinary flatbed scanners.

Carbon Black Nano-Strings can be conjugated to different antibodies for use in lateral flow immunoassay.

The immobilising procedure has to be optimised for each antibody by varying the:
  • Antibody concentration
  • Buffer pH and ionic strength
  • Storage and testing buffer





Downloads
  1. Directions for Use
Carbon Black Nano-Strings, 100 nm
Art. No Contents
0210 1x2 mL Carbon Black Nano-Strings, 100 nm
0211 1x10 mL Carbon Black Nano-Strings, 100 nm

Concentration: 10 mg/mL CBNS in 5 mM borate buffer pH 8.4
Maximum binding: 100-200 µg IgG/mg CBNS

A volume of 2 mL CBNS is sufficient for 10-15,000 immunochromatographic tests.

Downloads
  1. Directions for Use
Carbon Black Nano-Strings, 200 nm
Art. No Contents
0220 1x2 mL Carbon Black Nano-Strings, 200 nm
0221 1x10 mL Carbon Black Nano-Strings, 200 nm

Concentration: 10 mg/mL CBNS in 5 mM borate buffer pH 8.4
Maximum binding: 50-100 µg IgG/mg CBNS

A volume of 2 mL CBNS is sufficient for 10-15,000 immunochromatographic tests.

Downloads
See above.
Carbon Black Nano-Strings, Sample Pack
Art. No Contents
0240 1x1 mL Carbon Black Nano-Strings, 100 nm
1x1 mL Carbon Black Nano-Strings, 200 nm

Reference
Lönnberg, M., Drevin, M., Carlsson, J. Journal of Immunological Methods 339(2), 236-244 (2008) Ultra-sensitive immunochromatographic assay for quantitative determination of erythropoietin.